Combination of Docking-Based and Pharmacophore-Based Virtual Screening Identifies Novel Agonists That Target the Urotensin Receptor

The urotensin receptor (UT receptor), a G-protein-coupled receptor mediating urotensin-II and urotensin-II-related peptide signaling in the urotensinergic system, has multiple pharmacological activities. However, there is no drug targeting the UT receptor currently in clinical use, and the discovery...

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Detalles Bibliográficos
Autores principales: Li, Na, Yin, Lin, Chen, Xi, Shang, Jiamin, Liang, Meidai, Gao, Li, Qiang, Guifen, Xia, Jie, Du, Guanhua, Yang, Xiuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788431/
https://www.ncbi.nlm.nih.gov/pubmed/36557826
http://dx.doi.org/10.3390/molecules27248692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788431/
https://www.ncbi.nlm.nih.gov/pubmed/36557826
http://dx.doi.org/10.3390/molecules27248692

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