Design, Synthesis and Assay of Novel Methylxanthine–Alkynylmethylamine Derivatives as Acetylcholinesterase Inhibitors

Xanthine derivatives have been a great area of interest for the development of potent bioactive agents. Thirty-eight methylxanthine derivatives as acetylcholinesterase inhibitors (AChE) were designed and synthesized. Suzuki–Miyaura cross-coupling reactions of 8-chlorocaffeine with aryl(hetaryl)boron...

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Detalles Bibliográficos
Autores principales: Reshetnikov, Danila V., Ivanov, Igor D., Baev, Dmitry S., Rybalova, Tatyana V., Mozhaitsev, Evgenii S., Patrushev, Sergey S., Vavilin, Valentin A., Tolstikova, Tatyana G., Shults, Elvira E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788520/
https://www.ncbi.nlm.nih.gov/pubmed/36557921
http://dx.doi.org/10.3390/molecules27248787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788520/
https://www.ncbi.nlm.nih.gov/pubmed/36557921
http://dx.doi.org/10.3390/molecules27248787

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