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Replication Activities of Major 5′ Terminally Deleted Group-B Coxsackievirus RNA Forms Decrease PCSK2 mRNA Expression Impairing Insulin Maturation in Pancreatic Beta Cells

Emergence of 5′ terminally deleted coxsackievirus-B RNA forms (CVB-TD) have been associated with the development of human diseases. These CVB-TD RNA forms have been detected in mouse pancreas during acute or persistent experimental infections. To date, the impact of the replication activities of CVB...

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Detalles Bibliográficos
Autores principales: Callon, Domitille, Guedra, Aurélien, Lebreil, Anne-Laure, Heng, Laetitia, Bouland, Nicole, Fornès, Paul, Berri, Fatma, Andreoletti, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788552/
https://www.ncbi.nlm.nih.gov/pubmed/36560784
http://dx.doi.org/10.3390/v14122781