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Genome-Scale Metabolic Modeling Reveals Sequential Dysregulation of Glutathione Metabolism in Livers from Patients with Alcoholic Hepatitis

Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease for which there is no efficacious treatment aiding most patients. AH manifests differently in individuals, with some patients showing debilitating symptoms more so than others. Previous studies showed significant metabolic d...

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Detalles Bibliográficos
Autores principales: Manchel, Alexandra, Mahadevan, Radhakrishnan, Bataller, Ramon, Hoek, Jan B., Vadigepalli, Rajanikanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788589/
https://www.ncbi.nlm.nih.gov/pubmed/36557195
http://dx.doi.org/10.3390/metabo12121157