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MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF

Understanding how long noncoding RNAs (lncRNAs) cooperate with splicing factors (SFs) in alternative splicing (AS) control is fundamental to human biology and disease. We show that metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a well-documented AS-implicated lncRNA, regulates AS v...

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Detalles Bibliográficos
Autores principales: Miao, Hui, Wu, Fan, Li, Yu, Qin, Chenyu, Zhao, Yongyun, Xie, Mingfeng, Dai, Hongyuan, Yao, Hong, Cai, Haoyang, Wang, Qianhong, Song, Xu, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788761/
https://www.ncbi.nlm.nih.gov/pubmed/36563164
http://dx.doi.org/10.1126/sciadv.abq7289