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Prostaglandin EP3 receptor–expressing preoptic neurons bidirectionally control body temperature via tonic GABAergic signaling

The bidirectional controller of the thermoregulatory center in the preoptic area (POA) is unknown. Using rats, here, we identify prostaglandin EP3 receptor–expressing POA neurons (POA(EP3R) neurons) as a pivotal bidirectional controller in the central thermoregulatory mechanism. POA(EP3R) neurons ar...

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Detalles Bibliográficos
Autores principales: Nakamura, Yoshiko, Yahiro, Takaki, Fukushima, Akihiro, Kataoka, Naoya, Hioki, Hiroyuki, Nakamura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788766/
https://www.ncbi.nlm.nih.gov/pubmed/36563142
http://dx.doi.org/10.1126/sciadv.add5463