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Activation of circulating monocytes by low-density lipoprotein—a risk factor for osteoarthritis?
Synovial macrophages are key mediators of OA pathology, and skewing of macrophage phenotype in favour of an M1-like phenotype is thought to underlie the chronicity of synovial inflammation in OA. Components of the metabolic syndrome (MetS), such as dyslipidaemia, can affect macrophage phenotype and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788825/ https://www.ncbi.nlm.nih.gov/pubmed/35863051 http://dx.doi.org/10.1093/rheumatology/keac359 |