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Activation of circulating monocytes by low-density lipoprotein—a risk factor for osteoarthritis?

Synovial macrophages are key mediators of OA pathology, and skewing of macrophage phenotype in favour of an M1-like phenotype is thought to underlie the chronicity of synovial inflammation in OA. Components of the metabolic syndrome (MetS), such as dyslipidaemia, can affect macrophage phenotype and...

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Detalles Bibliográficos
Autores principales: Kruisbergen, Nik N L, van Gemert, Yvonne, Blom, Arjen B, van den Bosch, Martijn H J, van Lent, Peter L E M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788825/
https://www.ncbi.nlm.nih.gov/pubmed/35863051
http://dx.doi.org/10.1093/rheumatology/keac359