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Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor

This article presents a novel structure for efficient label free biosensing applications. The proposed device comprises of 6H-Silicon Carbide based double gate Schottky Barrier FET with two cavities to detect the biomolecules. Using Atlas TCAD simulations, it has been verified that the proposed devi...

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Autores principales: Rashid, Shazia, Bashir, Faisal, Khanday, Farooq A., Beigh, M. Rafiq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788864/
http://dx.doi.org/10.1007/s12633-022-02273-7
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author Rashid, Shazia
Bashir, Faisal
Khanday, Farooq A.
Beigh, M. Rafiq
author_facet Rashid, Shazia
Bashir, Faisal
Khanday, Farooq A.
Beigh, M. Rafiq
author_sort Rashid, Shazia
collection PubMed
description This article presents a novel structure for efficient label free biosensing applications. The proposed device comprises of 6H-Silicon Carbide based double gate Schottky Barrier FET with two cavities to detect the biomolecules. Using Atlas TCAD simulations, it has been verified that the proposed device has the maximum ON current sensitivity of 1.02 × 10(5), transconductance sensitivity of 7.741 × 10(4), I(ON)/I(OFF) sensitivity of 31.4, sub-threshold swing sensitivity of 77.19 mV/decade and threshold voltage sensitivity of 34.54 mV for neutral biomolecule with K = 12. Similar simulations have also been performed for different charged biomolecules, varying from ± 5 × 10(10) C/cm(2) to ± 1 × 10(12) C/cm(2). Besides, the proposed biosensor shows exceptional performance in terms of ON-current selectivity and sub-threshold swing selectivity. Finally, to check the device response for the changing input parameters, linearity of the biosensor has been analyzed. The achieved near-unity value of the Pearson’s fitness coefficient signifies the strong positive correlation between I(ON)/I(OFF) and dielectric property of the biomolecules.
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spelling pubmed-97888642022-12-27 Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor Rashid, Shazia Bashir, Faisal Khanday, Farooq A. Beigh, M. Rafiq Silicon Original Paper This article presents a novel structure for efficient label free biosensing applications. The proposed device comprises of 6H-Silicon Carbide based double gate Schottky Barrier FET with two cavities to detect the biomolecules. Using Atlas TCAD simulations, it has been verified that the proposed device has the maximum ON current sensitivity of 1.02 × 10(5), transconductance sensitivity of 7.741 × 10(4), I(ON)/I(OFF) sensitivity of 31.4, sub-threshold swing sensitivity of 77.19 mV/decade and threshold voltage sensitivity of 34.54 mV for neutral biomolecule with K = 12. Similar simulations have also been performed for different charged biomolecules, varying from ± 5 × 10(10) C/cm(2) to ± 1 × 10(12) C/cm(2). Besides, the proposed biosensor shows exceptional performance in terms of ON-current selectivity and sub-threshold swing selectivity. Finally, to check the device response for the changing input parameters, linearity of the biosensor has been analyzed. The achieved near-unity value of the Pearson’s fitness coefficient signifies the strong positive correlation between I(ON)/I(OFF) and dielectric property of the biomolecules. Springer Netherlands 2022-12-23 2023 /pmc/articles/PMC9788864/ http://dx.doi.org/10.1007/s12633-022-02273-7 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Paper
Rashid, Shazia
Bashir, Faisal
Khanday, Farooq A.
Beigh, M. Rafiq
Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title_full Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title_fullStr Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title_full_unstemmed Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title_short Double Gate 6H-Silicon Carbide Schottky Barrier FET as Dielectrically Modulated Label Free Biosensor
title_sort double gate 6h-silicon carbide schottky barrier fet as dielectrically modulated label free biosensor
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788864/
http://dx.doi.org/10.1007/s12633-022-02273-7
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