Glycemic control releases regenerative potential of pancreatic beta cells blocked by severe hyperglycemia

Diabetogenic ablation of beta cells in mice triggers a regenerative response whereby surviving beta cells proliferate and euglycemia is regained. Here, we identify and characterize heterogeneity in response to beta cell ablation. Efficient beta cell elimination leading to severe hyperglycemia (>2...

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Detalles Bibliográficos
Autores principales: Furth-Lavi, Judith, Hija, Ayat, Tornovsky-Babeay, Sharona, Mazouz, Adi, Dahan, Tehila, Stolovich-Rain, Miri, Klochendler, Agnes, Dor, Yuval, Avrahami, Dana, Glaser, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789023/
https://www.ncbi.nlm.nih.gov/pubmed/36450253
http://dx.doi.org/10.1016/j.celrep.2022.111719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789023/
https://www.ncbi.nlm.nih.gov/pubmed/36450253
http://dx.doi.org/10.1016/j.celrep.2022.111719

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