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Thousands of human non-AUG extended proteoforms lack evidence of evolutionary selection among mammals

The synthesis of most proteins begins at AUG codons, yet a small number of non-AUG initiated proteoforms are also known. Here we analyse a large number of publicly available Ribo-seq datasets to identify novel, previously uncharacterised non-AUG proteoforms using Trips-Viz implementation of a novel...

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Detalles Bibliográficos
Autores principales: Fedorova, Alla D., Kiniry, Stephen J., Andreev, Dmitry E., Mudge, Jonathan M., Baranov, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789052/
https://www.ncbi.nlm.nih.gov/pubmed/36564405
http://dx.doi.org/10.1038/s41467-022-35595-6