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The bile acid TUDCA reduces age-related hyperinsulinemia in mice

Aging is associated with glucose metabolism disturbances, such as insulin resistance and hyperinsulinemia, which contribute to the increased prevalence of type 2 diabetes (T2D) and its complications in the elderly population. In this sense, some bile acids have emerged as new therapeutic targets to...

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Detalles Bibliográficos
Autores principales: Zangerolamo, Lucas, Carvalho, Marina, Barssotti, Leticia, Soares, Gabriela M., Marmentini, Carine, Boschero, Antonio C., Barbosa, Helena Cristina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789133/
https://www.ncbi.nlm.nih.gov/pubmed/36564463
http://dx.doi.org/10.1038/s41598-022-26915-3