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The bile acid TUDCA reduces age-related hyperinsulinemia in mice
Aging is associated with glucose metabolism disturbances, such as insulin resistance and hyperinsulinemia, which contribute to the increased prevalence of type 2 diabetes (T2D) and its complications in the elderly population. In this sense, some bile acids have emerged as new therapeutic targets to...
Autores principales: | Zangerolamo, Lucas, Carvalho, Marina, Barssotti, Leticia, Soares, Gabriela M., Marmentini, Carine, Boschero, Antonio C., Barbosa, Helena Cristina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789133/ https://www.ncbi.nlm.nih.gov/pubmed/36564463 http://dx.doi.org/10.1038/s41598-022-26915-3 |
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