Ts66Yah, a mouse model of Down syndrome with improved construct and face validity

Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21). The understanding of genotype–phenotype relationships, the identification of driver genes and various proofs of concept for therapeutics have benefited from mouse models. The premier model, named Ts(17(16))65Dn/J (Ts65Dn), displ...

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Detalles Bibliográficos
Autores principales: Duchon, Arnaud, del Mar Muñiz Moreno, Maria, Chevalier, Claire, Nalesso, Valérie, Andre, Philippe, Fructuoso-Castellar, Marta, Mondino, Mary, Po, Chrystelle, Noblet, Vincent, Birling, Marie-Christine, Potier, Marie-Claude, Herault, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789398/
https://www.ncbi.nlm.nih.gov/pubmed/36374158
http://dx.doi.org/10.1242/dmm.049721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789398/
https://www.ncbi.nlm.nih.gov/pubmed/36374158
http://dx.doi.org/10.1242/dmm.049721

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