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A DUSP6 inhibitor suppresses inflammatory cardiac remodeling and improves heart function after myocardial infarction

Acute myocardial infarction (MI) results in loss of cardiomyocytes and abnormal cardiac remodeling with severe inflammation and fibrosis. However, how cardiac repair can be achieved by timely resolution of inflammation and cardiac fibrosis remains incompletely understood. Our previous findings have...

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Detalles Bibliográficos
Autores principales: Zhang, Zongwang, Chen, Yang, Zheng, Lixia, Du, Jianyong, Wei, Shicheng, Zhu, Xiaojun, Xiong, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789401/
https://www.ncbi.nlm.nih.gov/pubmed/36478044
http://dx.doi.org/10.1242/dmm.049662