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Effect of Rifampicin on the Pharmacokinetics of Evogliptin in Healthy Volunteers

PURPOSE: Evogliptin (DA-1229) is a novel, potent, and selective dipeptidyl peptidase 4 (DPP-4) inhibitor for treating type 2 diabetes mellitus. This study investigates the effect of rifampicin on evogliptin pharmacokinetics. PATIENTS AND METHODS: An open-label, crossover, one-sequence study was cond...

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Detalles Bibliográficos
Autores principales: Shin, Yesong, Choi, Chungam, Oh, Eun Sil, Kim, Choon Ok, Park, Kyungsoo, Park, Min Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789683/
https://www.ncbi.nlm.nih.gov/pubmed/36573067
http://dx.doi.org/10.2147/DDDT.S383157