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Activation of the RMTg Nucleus by Chemogenetic Techniques Alleviates the Learning and Memory Impairment in APP/PS1 Mice

OBJECTIVE: There is a relationship between non-rapid eye movement (NREM) sleep and Alzheimer’s disease (AD). The rostromedial tegmental nucleus (RMTg) is activated can enhance NREM. Therefore, our experiment was designed to investigate the effects of activation of RMTg by chemical genetic techniques...

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Detalles Bibliográficos
Autores principales: Zheng, Ling, Wang, Zhenjie, Liu, Yujia, Zhao, Jiapei, Huang, Saie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789721/
https://www.ncbi.nlm.nih.gov/pubmed/36573138
http://dx.doi.org/10.2147/NDT.S388832