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SD(2): spatially resolved transcriptomics deconvolution through integration of dropout and spatial information

MOTIVATION: Unveiling the heterogeneity in the tissues is crucial to explore cell–cell interactions and cellular targets of human diseases. Spatial transcriptomics (ST) supplies spatial gene expression profile which has revolutionized our biological understanding, but variations in cell-type proport...

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Detalles Bibliográficos
Autores principales: Li, Haoyang, Li, Hanmin, Zhou, Juexiao, Gao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789790/
https://www.ncbi.nlm.nih.gov/pubmed/36063455
http://dx.doi.org/10.1093/bioinformatics/btac605