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Separation of long-stranded RNAs by RP-HPLC using an octadecyl-based column with super-wide pores

Messenger ribonucleic acids (mRNAs) have been used in vaccines for various diseases and are attracting attention as a new pharmaceutical paradigm. The purification of mRNAs is necessary because various impurities, such as template DNAs and transcription enzymes, remain in the crude product after mRN...

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Detalles Bibliográficos
Autores principales: Kuwayama, Tomomi, Ozaki, Makoto, Shimotsuma, Motoshi, Hirose, Tsunehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789886/
https://www.ncbi.nlm.nih.gov/pubmed/36566342
http://dx.doi.org/10.1007/s44211-022-00253-w