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Separation of long-stranded RNAs by RP-HPLC using an octadecyl-based column with super-wide pores
Messenger ribonucleic acids (mRNAs) have been used in vaccines for various diseases and are attracting attention as a new pharmaceutical paradigm. The purification of mRNAs is necessary because various impurities, such as template DNAs and transcription enzymes, remain in the crude product after mRN...
Autores principales: | Kuwayama, Tomomi, Ozaki, Makoto, Shimotsuma, Motoshi, Hirose, Tsunehisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789886/ https://www.ncbi.nlm.nih.gov/pubmed/36566342 http://dx.doi.org/10.1007/s44211-022-00253-w |
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