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Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway

BACKGROUND: Neuroinflammation and neuronal apoptosis are closely associated with a poor prognosis in patients with subarachnoid hemorrhage (SAH). We investigated the role of C–C motif chemokine receptor 2 (CCR2) in SAH. METHODS: Pre-processed RNA-seq transcriptome datasets GSE167110 and GSE79416 fro...

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Detalles Bibliográficos
Autores principales: Tian, Qi, Guo, Yujia, Feng, Shi, Liu, Chengli, He, Peibang, Wang, Jianfeng, Han, Wenrui, Yang, Chen, Zhang, Zhan, Li, Mingchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789920/
https://www.ncbi.nlm.nih.gov/pubmed/36566220
http://dx.doi.org/10.1186/s12974-022-02676-8