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An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning

Dendrites of hippocampal CA1 pyramidal cells amplify clustered glutamatergic input by activation of voltage-gated sodium channels and N-methyl-D-aspartate receptors (NMDARs). NMDAR activity depends on the presence of NMDAR co-agonists such as D-serine, but how co-agonists influence dendritic integra...

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Detalles Bibliográficos
Autores principales: Bohmbach, Kirsten, Masala, Nicola, Schönhense, Eva M., Hill, Katharina, Haubrich, André N., Zimmer, Andreas, Opitz, Thoralf, Beck, Heinz, Henneberger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789958/
https://www.ncbi.nlm.nih.gov/pubmed/36566254
http://dx.doi.org/10.1038/s41467-022-35620-8