UHRF1-mediated ferroptosis promotes pulmonary fibrosis via epigenetic repression of GPX4 and FSP1 genes

Pulmonary fibrosis (PF), as an end-stage clinical phenotype of interstitial lung diseases (ILDs), is frequently initiated after alveolar injury, in which ferroptosis has been identified as a critical event aggravating the pathophysiological progression of this disease. Here in, a comprehensive analy...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Cheng, Demin, Wang, Yue, Xi, Sichuan, Wang, Ting, Sun, Wenqing, Li, Guanru, Ma, Dongyu, Zhou, Siyun, Li, Ziwei, Ni, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789966/
https://www.ncbi.nlm.nih.gov/pubmed/36566325
http://dx.doi.org/10.1038/s41419-022-05515-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789966/
https://www.ncbi.nlm.nih.gov/pubmed/36566325
http://dx.doi.org/10.1038/s41419-022-05515-z

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