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Improved β-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes

Lipoprotein lipase (LPL) hydrolyzes the triglyceride core of lipoproteins and also functions as a bridge, allowing for lipoprotein and cholesterol uptake. Transgenic mice expressing LPL in adipose tissue under the control of the adiponectin promoter (AdipoQ-LPL) have improved glucose metabolism when...

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Detalles Bibliográficos
Autores principales: Memetimin, Hasiyet, Zhu, Beibei, Lee, Sangderk, Katz, Wendy S., Kern, Philip A., Finlin, Brian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789969/
https://www.ncbi.nlm.nih.gov/pubmed/36566329
http://dx.doi.org/10.1038/s41598-022-26995-1