A genome-wide CRISPR screen identifies WDFY3 as a regulator of macrophage efferocytosis

Phagocytic clearance of dying cells, termed efferocytosis, is essential for maintaining tissue homeostasis, yet our understanding of efferocytosis regulation remains incomplete. Here we perform a FACS-based, genome-wide CRISPR knockout screen in primary mouse macrophages to search for novel regulato...

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Detalles Bibliográficos
Autores principales: Shi, Jianting, Wu, Xun, Wang, Ziyi, Li, Fang, Meng, Yujiao, Moore, Rebecca M., Cui, Jian, Xue, Chenyi, Croce, Katherine R., Yurdagul, Arif, Doench, John G., Li, Wei, Zarbalis, Konstantinos S., Tabas, Ira, Yamamoto, Ai, Zhang, Hanrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789999/
https://www.ncbi.nlm.nih.gov/pubmed/36566259
http://dx.doi.org/10.1038/s41467-022-35604-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789999/
https://www.ncbi.nlm.nih.gov/pubmed/36566259
http://dx.doi.org/10.1038/s41467-022-35604-8

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