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Protein folding and unfolding: proline cis‐trans isomerization at the c subunits of F(1)F(O)‐ATPase might open a high conductance ion channel
The c subunits, which constitute the c‐ring apparatus of the F(1)F(O)‐ATPase, could be the main components of the mitochondrial permeability transition pore (mPTP). The well‐known modulator of the mPTP formation and opening is the cyclophilin D (CyPD), a peptidyl‐prolyl cis‐trans isomerase. On the l...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley & Sons, Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790210/ https://www.ncbi.nlm.nih.gov/pubmed/35532281 http://dx.doi.org/10.1002/prot.26383 |