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Cannabidiol impairs neural tube closure in mouse whole embryo culture

BACKGROUND: Cannabidiol (CBD) is a nonpsychoactive constituent of cannabis widely available as a dietary supplement. Previous reports that it impairs the retinoid, sonic hedgehog, and folate metabolism pathways raise concern that it may impair closure of the embryonic neural tube (NT), producing NT...

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Detalles Bibliográficos
Autores principales: Gheasuddin, Yosuf, Galea, Gabriel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790336/
https://www.ncbi.nlm.nih.gov/pubmed/35416425
http://dx.doi.org/10.1002/bdr2.2013