Epigenetic conditioning induces intergenerational resilience to dementia in a mouse model of vascular cognitive impairment

INTRODUCTION: Epigenetic stimuli induce beneficial or detrimental changes in gene expression, and consequently, phenotype. Some of these phenotypes can manifest across the lifespan—and even in subsequent generations. Here, we used a mouse model of vascular cognitive impairment and dementia (VCID) to...

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Detalles Bibliográficos
Autores principales: Belmonte, Krystal Courtney D., Holmgren, Eleanor B., Wills, Tiffany A., Gidday, Jeff M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790554/
https://www.ncbi.nlm.nih.gov/pubmed/35170835
http://dx.doi.org/10.1002/alz.12616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790554/
https://www.ncbi.nlm.nih.gov/pubmed/35170835
http://dx.doi.org/10.1002/alz.12616

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