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Epigenetic conditioning induces intergenerational resilience to dementia in a mouse model of vascular cognitive impairment
INTRODUCTION: Epigenetic stimuli induce beneficial or detrimental changes in gene expression, and consequently, phenotype. Some of these phenotypes can manifest across the lifespan—and even in subsequent generations. Here, we used a mouse model of vascular cognitive impairment and dementia (VCID) to...
Autores principales: | Belmonte, Krystal Courtney D., Holmgren, Eleanor B., Wills, Tiffany A., Gidday, Jeff M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790554/ https://www.ncbi.nlm.nih.gov/pubmed/35170835 http://dx.doi.org/10.1002/alz.12616 |
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