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Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids

BACKGROUND AND AIMS: Cholangiocarcinoma (CCA) includes a heterogeneous group of biliary cancers with a dismal prognosis. We investigated if lipid metabolism is disrupted in CCA and its role in tumor proliferation. APPROACH AND RESULTS: The in vitro and in vivo tumorigenic capacity of five human CCA...

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Detalles Bibliográficos
Autores principales: Ruiz de Gauna, Mikel, Biancaniello, Francesca, González‐Romero, Francisco, Rodrigues, Pedro M., Lapitz, Ainhoa, Gómez‐Santos, Beatriz, Olaizola, Paula, Di Matteo, Sabina, Aurrekoetxea, Igor, Labiano, Ibone, Nieva‐Zuluaga, Ane, Benito‐Vicente, Asier, Perugorria, María J., Apodaka‐Biguri, Maider, Paiva, Nuno A., Sáenz de Urturi, Diego, Buqué, Xabier, Delgado, Igotz, Martín, César, Azkargorta, Mikel, Elortza, Felix, Calvisi, Diego F., Andersen, Jesper B., Alvaro, Domenico, Cardinale, Vincenzo, Bujanda, Luis, Banales, Jesús M., Aspichueta, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790564/
https://www.ncbi.nlm.nih.gov/pubmed/35030285
http://dx.doi.org/10.1002/hep.32344