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Copy‐number intratumor heterogeneity increases the risk of relapse in chemotherapy‐naive stage II colon cancer

Optimal selection of high‐risk patients with stage II colon cancer is crucial to ensure clinical benefit of adjuvant chemotherapy. Here, we investigated the prognostic value of genomic intratumor heterogeneity and aneuploidy for disease recurrence. We combined targeted sequencing, SNP arrays, fluore...

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Detalles Bibliográficos
Autores principales: Lahoz, Sara, Archilla, Ivan, Asensio, Elena, Hernández‐Illán, Eva, Ferrer, Queralt, López‐Prades, Sandra, Nadeu, Ferran, Del Rey, Javier, Sanz‐Pamplona, Rebeca, Lozano, Juan José, Castells, Antoni, Cuatrecasas, Miriam, Camps, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790656/
https://www.ncbi.nlm.nih.gov/pubmed/35066875
http://dx.doi.org/10.1002/path.5870