Cargando…

Calcium Channel α2δ1 is Essential for Pancreatic Tumor-Initiating Cells through Sequential Phosphorylation of PKM2

BACKGROUND & AIMS: Tumor-initiating cells (TICs) drive pancreatic cancer tumorigenesis, therapeutic resistance, and metastasis. However, TICs are highly plastic and heterogenous, which impede the robust identification and targeted therapy of such a population. The aim of this study is to identif...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jingtao, Tao, Ming, Zhao, Wei, Song, Qingru, Yang, Xiaodan, Li, Meng, Zhang, Yanhua, Xiu, Dianrong, Zhang, Zhiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791133/
https://www.ncbi.nlm.nih.gov/pubmed/36244646
http://dx.doi.org/10.1016/j.jcmgh.2022.10.006