A penetratin-derived peptide reduces the membrane permeabilization and cell toxicity of α-synuclein oligomers

Parkinson's disease is a neurodegenerative movement disorder associated with the intracellular aggregation of α-synuclein (α-syn). Cytotoxicity is mainly associated with the oligomeric species (αSOs) formed at early stages in α-syn aggregation. Consequently, there is an intense focus on the dis...

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Detalles Bibliográficos
Autores principales: Pirhaghi, Mitra, Frank, Signe Andrea, Alam, Parvez, Nielsen, Janni, Sereikaite, Vita, Gupta, Arpit, Strømgaard, Kristian, Andreasen, Maria, Sharma, Deepak, Saboury, Ali Akbar, Otzen, Daniel Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791135/
https://www.ncbi.nlm.nih.gov/pubmed/36370848
http://dx.doi.org/10.1016/j.jbc.2022.102688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791135/
https://www.ncbi.nlm.nih.gov/pubmed/36370848
http://dx.doi.org/10.1016/j.jbc.2022.102688

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