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Single-cell Transcriptomics Reveals Early Molecular and Immune Alterations Underlying the Serrated Neoplasia Pathway Toward Colorectal Cancer

BACKGROUND & AIMS: Approximately one-third of colorectal cancers develop from serrated lesions (SLs), including hyperplastic polyp (HP), sessile serrated lesion (SSL), traditional serrated adenoma (TSA), and SSL with dysplasia (SSLD) through the serrated neoplasia pathway, which progresses faste...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-Jie, Lu, Xiao-Fan, Chen, Huimin, Wang, Xin-Yuan, Cheng, Wenxuan, Zhang, Qing-Wei, Chen, Jin-Nan, Wang, Xiao-Yi, Jin, Jing-Zheng, Yan, Fang-Rong, Chen, Haoyan, Li, Xiao-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791140/
https://www.ncbi.nlm.nih.gov/pubmed/36216310
http://dx.doi.org/10.1016/j.jcmgh.2022.10.001