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Role of biotransformation in the diazinon-induced toxicity in HepG2 cells and antioxidant protection by tetrahydrocurcumin

Diazinon (DZN) is an insecticide extensively used to control pests in crops and animals. However, its indicriminated use may lead to liver damage in animals and humans. This study aimed to evaluate the toxicity of DZN (25–150 µM) on human hepatoblastoma (HepG2) cells after 24 and 48 h of exposure an...

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Detalles Bibliográficos
Autores principales: Miranda, Camila Araújo, Beretta, Eduardo Morais, Ferreira, Layra Araújo, da Silva, Emmily Sousa, Coimbra, Beatriz Zimermano, Pereira, Priscila Tartari, Miranda, Raul Ghiraldelli, Dorta, Daniel Junqueira, Rodrigues, Flávia Thomaz Verechia, Mingatto, Fábio Erminio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791245/
https://www.ncbi.nlm.nih.gov/pubmed/36578673
http://dx.doi.org/10.1016/j.toxrep.2022.12.005