Identification of DOT1L inhibitor in a screen for factors that promote dopaminergic neuron survival

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra region of the midbrain. Diagnostic criteria for PD require that at least two of three motor signs are observed: tremor, rigidity, and/or bradykin...

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Detalles Bibliográficos
Autores principales: Cui, Jun, Carey, Joseph, Reijo Pera, Renee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791259/
https://www.ncbi.nlm.nih.gov/pubmed/36578445
http://dx.doi.org/10.3389/fnagi.2022.1026468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791259/
https://www.ncbi.nlm.nih.gov/pubmed/36578445
http://dx.doi.org/10.3389/fnagi.2022.1026468

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