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Ring-stage growth arrest: Metabolic basis of artemisinin tolerance in Plasmodium falciparum

The emergence and spread of artemisinin-tolerant malaria parasites threatens malaria control programmes worldwide. Mutations in the propeller domain of the Kelch13 protein confer Plasmodium falciparum artemisinin resistance (ART-R). ART-R is linked to the reduced susceptibility of temporary growth-a...

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Detalles Bibliográficos
Autores principales: Yu, Xinyu, Wang, Changhong, Zhao, Yuemeng, Tang, Jianxia, Zhu, Meng, Platon, Lucien, Culleton, Richard, Zhu, Guoding, Ménard, Didier, Zhang, Qingfeng, Cao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791339/
https://www.ncbi.nlm.nih.gov/pubmed/36579133
http://dx.doi.org/10.1016/j.isci.2022.105725