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Ring-stage growth arrest: Metabolic basis of artemisinin tolerance in Plasmodium falciparum
The emergence and spread of artemisinin-tolerant malaria parasites threatens malaria control programmes worldwide. Mutations in the propeller domain of the Kelch13 protein confer Plasmodium falciparum artemisinin resistance (ART-R). ART-R is linked to the reduced susceptibility of temporary growth-a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791339/ https://www.ncbi.nlm.nih.gov/pubmed/36579133 http://dx.doi.org/10.1016/j.isci.2022.105725 |