Cargando…

Ring-stage growth arrest: Metabolic basis of artemisinin tolerance in Plasmodium falciparum

The emergence and spread of artemisinin-tolerant malaria parasites threatens malaria control programmes worldwide. Mutations in the propeller domain of the Kelch13 protein confer Plasmodium falciparum artemisinin resistance (ART-R). ART-R is linked to the reduced susceptibility of temporary growth-a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xinyu, Wang, Changhong, Zhao, Yuemeng, Tang, Jianxia, Zhu, Meng, Platon, Lucien, Culleton, Richard, Zhu, Guoding, Ménard, Didier, Zhang, Qingfeng, Cao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791339/ https://www.ncbi.nlm.nih.gov/pubmed/36579133 http://dx.doi.org/10.1016/j.isci.2022.105725

Ejemplares similares

Genome-wide landscape of ApiAP2 transcription factors reveals a heterochromatin-associated regulatory network during Plasmodium falciparum blood-stage development
por: Shang, Xiaomin, et al.
Publicado: (2022)

A cascade of transcriptional repression determines sexual commitment and development in Plasmodium falciparum
por: Shang, Xiaomin, et al.
Publicado: (2021)

Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure
por: Ménard, Sandie, et al.
Publicado: (2015)

Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia
por: Dwivedi, Ankit, et al.
Publicado: (2017)

Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
por: Xie, Stanley C., et al.
Publicado: (2016)

Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage
por: Kümpornsin, Krittikorn, et al.
Publicado: (2021)

Plasmodium falciparum: multifaceted resistance to artemisinins
por: Paloque, Lucie, et al.
Publicado: (2016)

Optimization of CRISPR/Cas System for Improving Genome Editing Efficiency in Plasmodium falciparum
por: Zhao, Yuemeng, et al.
Publicado: (2021)

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand–Myanmar Border
por: Boullé, Mikael, et al.
Publicado: (2016)

Artemisinin exposure at the ring or trophozoite stage impacts Plasmodium falciparum sexual conversion differently
por: Portugaliza, Harvie P, et al.
Publicado: (2020)

Ring stage dormancy of Plasmodium falciparum tolerant to artemisinin and its analogues – A genetically regulated “Sleeping Beauty”
por: Auparakkitanon, Saranya, et al.
Publicado: (2023)

Laboratory Detection of Artemisinin-Resistant Plasmodium falciparum
por: Chotivanich, Kesinee, et al.
Publicado: (2014)

Mechanisms of artemisinin resistance in Plasmodium falciparum malaria
por: Suresh, Niraja, et al.
Publicado: (2018)

Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China
por: Lu, Feng, et al.
Publicado: (2017)

A Novel Single-Nucleotide Polymorphism Loop Mediated Isothermal Amplification Assay for Detection of Artemisinin-Resistant Plasmodium falciparum Malaria
por: Mohon, Abu Naser, et al.
Publicado: (2018)

Imidazolopiperazines Kill both Rings and Dormant Rings in Wild-Type and K13 Artemisinin-Resistant Plasmodium falciparum In Vitro
por: Dembele, Laurent, et al.
Publicado: (2018)

Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania
por: Mugittu, Kefas, et al.
Publicado: (2006)

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
por: Miotto, Olivo, et al.
Publicado: (2013)

Artemisinin‐naphthoquine for treating uncomplicated Plasmodium falciparum malaria
por: Isba, Rachel, et al.
Publicado: (2015)

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum
por: Wang, Jigang, et al.
Publicado: (2015)

Plasmodium falciparum rosetting protects schizonts against artemisinin
por: Lee, Wenn-Chyau, et al.
Publicado: (2021)

Plasmodium falciparum resistance to artemisinin-based combination therapies
por: Ward, Kurt E, et al.
Publicado: (2022)

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites
por: Nardella, Flore, et al.
Publicado: (2019)

A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum
por: Simmons, Caroline, et al.
Publicado: (2023)

Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa
por: Chen, Jing, et al.
Publicado: (2022)

The Antagonizing Role of Heme in the Antimalarial Function of Artemisinin: Elevating Intracellular Free Heme Negatively Impacts Artemisinin Activity in Plasmodium falciparum
por: Zhu, Pan, et al.
Publicado: (2022)

Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar
por: Ménard, Didier, et al.
Publicado: (2007)

The Architectural Factor HMGB1 Is Involved in Genome Organization in the Human Malaria Parasite Plasmodium falciparum
por: Lu, Binbin, et al.
Publicado: (2021)

Malaria in the horn of Africa: The ongoing battle against drug resistance
por: Platon, Lucien, et al.
Publicado: (2023)

Full-Length Transcriptome Analysis of Plasmodium falciparum by Single-Molecule Long-Read Sequencing
por: Yang, Mengquan, et al.
Publicado: (2021)

Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity
por: Kite, Whitney A., et al.
Publicado: (2016)

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria
por: Mbengue, Alassane, et al.
Publicado: (2015)

Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum
por: Sibley, Carol Hopkins
Publicado: (2015)

Decreased In Vitro Artemisinin Sensitivity of Plasmodium falciparum across India
por: Chakrabarti, Rimi, et al.
Publicado: (2019)

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
por: Fola, Abebe A., et al.
Publicado: (2023)

Lack of artemisinin resistance in Plasmodium falciparum in northwest Benin after 10 years of use of artemisinin-based combination therapy
por: Ogouyèmi-Hounto, Aurore, et al.
Publicado: (2016)

The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study
por: Imwong, Mallika, et al.
Publicado: (2017)

Assessment of artemisinin tolerance in Plasmodium falciparum clinical isolates in children with uncomplicated malaria in Ghana
por: Ahorhorlu, Samuel Yao, et al.
Publicado: (2023)

Sustained Ex Vivo Susceptibility of Plasmodium falciparum to Artemisinin Derivatives but Increasing Tolerance to Artemisinin Combination Therapy Partner Quinolines in The Gambia
por: Amambua-Ngwa, Alfred, et al.
Publicado: (2017)

Persistence of mRNA indicative of Plasmodium falciparum ring-stage parasites 42 days after artemisinin and non-artemisinin combination therapy in naturally infected Malians
por: Mahamar, Almahamoudou, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p6npni0lmv7s46hd6qpkskjk72