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Distance covariance entropy reveals primed states and bifurcation dynamics in single-cell RNA-Seq data

Cell-fate transitions are fundamental to development and differentiation. Studying them with single-cell omic data is important to advance our understanding of the cell-fate commitment process, yet this remains challenging. Here we present a computational method called DICE, which analyzes the entro...

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Detalles Bibliográficos
Autores principales: Luo, Qi, Maity, Alok K., Teschendorff, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791356/
https://www.ncbi.nlm.nih.gov/pubmed/36578319
http://dx.doi.org/10.1016/j.isci.2022.105709