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Prostate cancer small extracellular vesicles participate in androgen-independent transformation of prostate cancer by transferring let-7a-5p

OBJECTIVES: Androgen deprivation therapy (ADT) is a standard treatment for advanced prostate cancer (PCa). However, after 2–3 years ADT treatment, prostate cancer inevitably transits from androgen-dependent PCa (ADPC) to androgen-independent PCa (AIPC), which has a poor prognosis owing to its unclea...

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Detalles Bibliográficos
Autores principales: Lei, Lin, Yu, Lijuan, Fan, Weixiao, Hao, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791359/
https://www.ncbi.nlm.nih.gov/pubmed/36578414
http://dx.doi.org/10.1016/j.heliyon.2022.e12114