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Yeast 9-1-1 complex acts as a sliding clamp for DNA synthesis by DNA polymerase ε

Eukaryotic cells harbor two DNA-binding clamps, proliferating cell nuclear antigen (PCNA), and another clamp commonly referred to as 9-1-1 clamp. In contrast to the essential role of PCNA in DNA replication as a sliding clamp for DNA polymerase (Pol) δ, no such role in DNA synthesis has been identif...

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Detalles Bibliográficos
Autores principales: Acharya, Narottam, Prakash, Louise, Prakash, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791402/
https://www.ncbi.nlm.nih.gov/pubmed/36410434
http://dx.doi.org/10.1016/j.jbc.2022.102727