Biphasic transcriptional and posttranscriptional regulation of MYB by androgen signaling mediates its growth control in prostate cancer

MYB, a proto-oncogene, is overexpressed in prostate cancer (PCa) and promotes its growth, aggressiveness, and resistance to androgen-deprivation therapy. Here, we examined the effect of androgen signaling on MYB expression and delineated the underlying molecular mechanisms. Paralleling a dichotomous...

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Detalles Bibliográficos
Autores principales: Acharya, Srijan, Anand, Shashi, Khan, Mohammad Aslam, Zubair, Haseeb, Srivastava, Sanjeev Kumar, Singh, Seema, Singh, Ajay Pratap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791434/
https://www.ncbi.nlm.nih.gov/pubmed/36410437
http://dx.doi.org/10.1016/j.jbc.2022.102725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791434/
https://www.ncbi.nlm.nih.gov/pubmed/36410437
http://dx.doi.org/10.1016/j.jbc.2022.102725

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