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Experimental evidence of a limited impact of new-generation perfluoroalkyl substance C6O4 on differentiating human dopaminergic neurons from induced pluripotent stem cells

Perfluoroalkyl substances (PFASs) are persistent pollutants, raising concerns for human health. Legacy PFAS perfluoro-octanoic acid (PFOA) accumulate in brains of people at high environmental exposure, especially in areas enriched with dopaminergic neurons (DN). In vitro exposure to 10 ng/mL PFOA fo...

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Detalles Bibliográficos
Autores principales: Di Nisio, Andrea, Trevisan, Marta, Dall’Acqua, Stefano, Pannella, Micaela, Pappalardo, Claudia, Ferlin, Alberto, Foresta, Carlo, De Toni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791692/
https://www.ncbi.nlm.nih.gov/pubmed/36578672
http://dx.doi.org/10.1016/j.toxrep.2022.12.006