ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein

BACKGROUND: Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB). Such ligands are more sensitive and specific than small-molecule ligands at detecting Aβ patholog...

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Detalles Bibliográficos
Autores principales: Bonvicini, Gillian, Syvänen, Stina, Andersson, Ken G., Haaparanta-Solin, Merja, López-Picón, Francisco, Sehlin, Dag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791759/
https://www.ncbi.nlm.nih.gov/pubmed/36567338
http://dx.doi.org/10.1186/s40035-022-00324-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791759/
https://www.ncbi.nlm.nih.gov/pubmed/36567338
http://dx.doi.org/10.1186/s40035-022-00324-y

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