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ImmunoPET imaging of amyloid-beta in a rat model of Alzheimer’s disease with a bispecific, brain-penetrating fusion protein

BACKGROUND: Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB). Such ligands are more sensitive and specific than small-molecule ligands at detecting Aβ patholog...

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Detalles Bibliográficos
Autores principales:	Bonvicini, Gillian, Syvänen, Stina, Andersson, Ken G., Haaparanta-Solin, Merja, López-Picón, Francisco, Sehlin, Dag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791759/ https://www.ncbi.nlm.nih.gov/pubmed/36567338 http://dx.doi.org/10.1186/s40035-022-00324-y

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