ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) shares risk factors with cardiovascular disease (CVD) and dysregulated cholesterol metabolism is a mechanism common to both diseases. Cholesterol efflux capacity (CEC) is an ex vivo metric of plasma high-density lipoprotein (HDL) function and inversely predicts i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ko, Yi-An, Billheimer, Jeffrey T., Lyssenko, Nicholas N., Kueider-Paisley, Alexandra, Wolk, David A., Arnold, Steven E., Leung, Yuk Yee, Shaw, Leslie M., Trojanowski, John Q., Kaddurah-Daouk, Rima F., Kling, Mitchel A., Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791777/
https://www.ncbi.nlm.nih.gov/pubmed/36572909
http://dx.doi.org/10.1186/s13195-022-01119-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791777/
https://www.ncbi.nlm.nih.gov/pubmed/36572909
http://dx.doi.org/10.1186/s13195-022-01119-z

Ejemplares similares