Affinity purification of serum-derived anti-IA-2 autoantibodies in type 1 diabetes using a novel MBP-IA-2 fusion protein

Autoantibodies targeting epitopes contained within the intracellular domain (IC) of the protein phosphatase-like islet antigen 2 (IA-2) are a common marker of autoimmune type 1 diabetes (T1D), however the isolation of genuine, serum derived anti-IA-2 autoantibodies has proven challenging due to a la...

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Detalles Bibliográficos
Autores principales: Mendis, Thilini, Filipova, Barbora, Wang, Jing Jing, Pietropaolo, Massimo, Jackson, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791830/
https://www.ncbi.nlm.nih.gov/pubmed/36578528
http://dx.doi.org/10.1016/j.bbrep.2022.101413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791830/
https://www.ncbi.nlm.nih.gov/pubmed/36578528
http://dx.doi.org/10.1016/j.bbrep.2022.101413

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