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Effectiveness of Soluble CTLA-4-Fc in the Inhibition of Bone Marrow T-Cell Activation in Context of Indoleamine 2.3-Dioxygenase (IDO) and CD4(+)Foxp3(+) Treg Induction

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease with systemic inflammation finally resulting in damaged joints. One of the RA development models suggests bone marrow (BM) as a place of inflammation development further leading to disease progression. We aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Massalska, Magdalena, Ciechomska, Marzena, Kuca-Warnawin, Ewa, Burakowski, Tomasz, Kornatka, Anna, Radzikowska, Anna, Pawlak, Dariusz, Muz, Barbara, Loniewska-Lwowska, Adrianna, Palucha, Andrzej, Maldyk, Pawel, Maslinski, Wlodzimierz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792113/
https://www.ncbi.nlm.nih.gov/pubmed/36578517
http://dx.doi.org/10.2147/JIR.S359775