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CRISPRi-Mediated Gene Suppression Reveals Putative Reverse Transcriptase Gene PA0715 to Be a Global Regulator of Pseudomonas aeruginosa

PURPOSE: Pseudomonas aeruginosa is a common pathogen of infection in burn and trauma patients, and multi-drug resistant P. aeruginosa has become an increasingly important pathogen. Essential genes are key to the development of novel antibiotics. The PA0715 gene is a novel unidentified essential gene...

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Detalles Bibliográficos
Autores principales: Zhou, Dapeng, Huang, Guangtao, Xu, Guangchao, Xiang, Lijuan, Huang, Siyi, Chen, Xinchong, Zhang, Yixin, Wang, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792118/
https://www.ncbi.nlm.nih.gov/pubmed/36579125
http://dx.doi.org/10.2147/IDR.S384980