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CRISPRi-Mediated Gene Suppression Reveals Putative Reverse Transcriptase Gene PA0715 to Be a Global Regulator of Pseudomonas aeruginosa
PURPOSE: Pseudomonas aeruginosa is a common pathogen of infection in burn and trauma patients, and multi-drug resistant P. aeruginosa has become an increasingly important pathogen. Essential genes are key to the development of novel antibiotics. The PA0715 gene is a novel unidentified essential gene...
Autores principales: | Zhou, Dapeng, Huang, Guangtao, Xu, Guangchao, Xiang, Lijuan, Huang, Siyi, Chen, Xinchong, Zhang, Yixin, Wang, Dali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792118/ https://www.ncbi.nlm.nih.gov/pubmed/36579125 http://dx.doi.org/10.2147/IDR.S384980 |
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