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DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife

DNA methylation-based (DNAm) measures of biological aging associate with increased risk of morbidity and mortality, but their links with cognitive decline are less established. This study examined changes over a 16-year interval in epigenetic clocks (the traditional and principal components [PC]-bas...

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Detalles Bibliográficos
Autores principales: Reed, Rebecca G., Carroll, Judith E., Marsland, Anna L., Manuck, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792211/
https://www.ncbi.nlm.nih.gov/pubmed/36374219
http://dx.doi.org/10.18632/aging.204376